何悦，教授，硕士生导师（招生方向：食品科学【专业代码083201】）

主要经历

• 09/2004-06/2008，华中师范大学，学士
• 09/2008-06/2013，武汉大学，博士
• 09/2014-08/2015，台湾清华大学，博士后
• 07/2013-06/2018，西南大学柑桔研究所，副研究员
• 07/2018-至今，西南大学柑桔研究所，教授

主持项目：

• 基于核酸适配体的赭曲霉毒素A快速检测技术研究，西南大学基本科研业务费，2014年- 2016年，主持。
• 利用血糖仪构建便携式传感器用于农业生态环境中重金属的检测研究，西南大学基本科研业务费，2015年- 2017年，主持。
• 基于核酸适配体和新型指数放大技术快速检测赭曲霉毒素A，重庆市自然科学基金项目，2015年- 2017年，主持。
• 基于氧化石墨烯和核酸末端保护的蛋白质传感新方法研究，国家自然基金项目/青年基金，2015年- 2017年，主持。
• 基于纳米酶的新型级联比色传感器用于赭曲霉毒素A的检测，国家柑桔工程技术研究中心开放课题，2019年-2021年，主持。
• 基于纳米酶的智能探针快速灵敏检测出血性大肠杆菌O157：H7 的研究，西南大学基本科研业务费，2019年-2020年，主持。
• 农产品中有害病原微生物快速检测试剂盒的研制，重庆市技术创新与应用示范（社会民生类）一般项目，2018年-2020年，主持。

代表性成果：

BOOK CHAPTER

• Yue He, Andrea del Valle, Yufen Huang*. Book chapter “Cell-specific aptamers for targeted therapy” in “Aptamers Selected by Cell-SELEX for Theranostics”, 1st ed. Springer, 2015. (Editors: Weihong Tan and Xiaohong Fang)

PUBLICATIONS IN PEER-REVIEWED INTERNATIONAL JOURNAL

2020年

• Jing Zhou, Fengyu Tian, Ruijie Fu, Yujun Yang, Bining Jiao, and Yue He*. Enzyme-Nanozyme Cascade Reaction-Mediated Etching of Gold Nanorods for the Detection of Escherichia coli. ACS Appl. Nano Mater. 2020, 3, 9016?9025.
• Jing Zhou, Ruijie Fu, Fengyu Tian, Yujun Yang, Bining Jiao, and Yue He*. Dual Enzyme-Induced Au-Ag Alloy Nanorods as Colorful Chromogenic Substrates for Sensitive Detection of Staphylococcus aureus. ACS Appl. Bio Mater. 2020, 3, 9, 6103–6109.

• Fengyu Tian, Ruijie Fu, Jing Zhou, Yongliang Cui, Yaohai Zhang, Bining Jiao*, Yue He*. Manganese dioxide nanosheet-mediated etching of gold nanorods for a multicolor colorimetric assay of total antioxidant capacity. Sensors & Actuators: B. Chemical, 2020, 321, 128604.
  

• Fengyu Tian, Jing Zhou, Ruijie Fu, Yongliang Cui, Qiyang Zhao, Bining Jiao, Yue He*. Multicolor colorimetric detection of ochratoxin A via structure-switching aptamer and enzyme-induced metallization of gold nanorods. Food Chemistry, 2020,320, 126607.
• Yue He*, Fengyu Tian, Jing Zhou, Qiyang Zhao, Ruijie Fu, Bining Jiao*. Colorimetric aptasensor for ochratoxin A detection based on enzyme-induced gold nanoparticle aggregation. Journal of Hazardous Materials, 2020, 388, 121758.

2019年

• Fengyu Tian, Jing Zhou, Bining Jiao and Yue He*. A nanozyme-based cascade colorimetric aptasensor for amplified detection of ochratoxin A.Nanoscale, 2019, 11, 9547. (IF=6.97)
• Yue He*, Fengyu Tian, Jing Zhou, Bining Jiao*. A fluorescent aptasensor for ochratoxin A detection based on enzymatically generated copper nanoparticles with a polythymine scaffold.Microchimica Acta, 2019, 186:199.(IF=5.479)
• Yue He*, Fengyu Tian, Jing Zhou, Bining Jiao*. Alkaline phosphatase determination via regulation of enzymatically generated poly(thymine) as a template for fluorescent copper nanoparticle formation.Analytical and Bioanalytical Chemistry, 2019, Volume 411, Issue 17, pp 3811–3818.(IF=3.307)
• Fengyu Tian, Jing Zhou, Jing Ma, Siyuan Liu, Bining Jiao, Yue He*.MnO2 nanosheets as oxidase mimics for colorimetric detection of alkaline phosphatase activity.Microchimica Acta, 2019, 186:408. (IF=5.479)
• 田风玉，周静，何悦*，焦必宁*.光学适配体传感器在赭曲霉毒素A 检测中的应用研究进展.食品与发酵工业.2019, 45, 242-249.
• 周静，田风玉，焦必宁*，何悦*.基于纳米材料的可视化比色检测技术在食源性致病菌检测中的应用研究进展.食品与发酵工业.2019.https://doi.org/10.13995/j.cnki.11-1802/ts.019960.

2018年

• Yue He, Bining Jiao. Detection of biotin-streptavidin interactions based onpoly(thymine)-templated copper nanoparticles coupled with ExoIII-aided DNA recycling amplification. Sensors and Actuators B 265 (2018) 387–393. (IF=6.393)

2017年

• .Yue He, Andrea del Valle, Yu Qian and Yu-Fen Huang*. Near infrared light-mediated enhancement of reactive oxygen species generation through electron transfer from graphene oxide to iron hydroxide/oxide. Nanoscale, 2017, 9, 1559-1566. （IF=7.760）
• Yue He, Fen Cheng, Daiwen Pang, Hongwu Tang*. Colorimetric and visual determination of DNase I activity using gold nanoparticles as an indicator. Microchim Acta, 2017, 184, 101-106.（IF=4.831）
• Yue He*, Chengqiu Wang, Qiyang Zhao, Yaohai Zhang, Aihua Chen, Junxiao Pang, Qi Fang, Yongliang Cui, Bining Jiao. Facile and sensitive fluorescence sensing of alkaline phosphatase activity using NMM/G-quadruplex. Talanta, 2017, 172, 171-175.（IF=4.035）
• Yue He*, Bining Jiao. Determination of the activity of alkaline phosphatase based on the use of ssDNA-templated fluorescent silver nanoclusters and on enzyme-triggered silver reduction. Microchim Acta, 2017, 184, 4167-4173.（IF=4.831）

2016年

• Yue He*, Bining Jiao. Detection of biotin-streptavidin interactions via terminal protection of small molecule linked DNA and the formation of fluorescent DNA-templated silver nanoclusters. Microchim Acta, 2016, 183, 3183-3189.（IF=4.831）
• Yue He*, Bining Jiao. Simple and convenient G-quadruplex-based fluorescent assayof biotin-streptavidin interaction via terminal protection of smallmolecule-linked DNA. Microchim Acta, 2016, 183, 3303-3309.（IF=4.831）
• Yue He*, Bining Jiao. DNA covalently linked to graphene oxide for biotin–streptavidin interaction assay. Talanta, 2017, 163, 140-145.（IF=4.035）

2015年

• Yue He*, Bining Jiao. High performance system for protein assays: synergistic effect of terminal protection strategy and graphene oxide platform. RSC Advances, 2015, 5, 101327.（IF=3.289）
• Yue He*, Bining Jiao. Simple and convenient G-quadruplex-based fluorescence assay of micrococcal nuclease activity. RSC Advances, 2015, 5, 104116.（IF=3.289）
• Fen Cheng, Yue He, Xiaojing Xing, Daidi Tan, Yi Lin, Daiwen Pang, Hongwu Tang*. A gold nanoparticle-based label free colorimetric aptasensor for adenosine deaminase detection and inhibition assay. Analyst, 2015, 140, 1572-1577. (Co-first author) （IF=4.033）
• Hao Xu, Chuang Chen, Yue He, Hongwu Tang*, Zhiling Zhang, Yan Li, Daiwen Pang, Analysis of Cancer Marker in Tissues with Hadamard Transform Fluorescence Spectral Microscopic Imaging, Journal of Fluorescence, 2015, 25, 397-402.（IF=1.601）

2014年

• Yue He*, Bining Jiao*. An ultrasensitive fluorometric platform for S1 nuclease assay based on cytochrome c. RSC Advances, 2014, 4, 35422. （IF=3.289）
• Yue He*, Bining Jiao*, Hongwu Tang. Interaction of single-stranded DNA with graphene oxide: fluorescence study and its application for S1 nuclease detection. RSC Advances, 2014, 4, 18294.（IF=3.289）

2013年

• Yue He, Xiaojing Xing, Hongwu Tang*, Daiwen Pang. Graphene oxide-based fluorescent biosensor for protein detection via terminal protection of small-molecule-linked DNA. Small, 2013, 9, 2097-2101.（IF=8.315）
• Yue He, Linghong Xiong, Xiaojing Xing, Hongwu Tang*, Daiwen Pang. An ultra-high sensitive platform for fluorescence detection of micrococcal nuclease based on graphene oxide. Biosensors and Bioelectronics, 2013, 42, 467-473.（IF=7.476）
• Daidi Tan, Yue He, Xiaojing Xing, Yu Zhao, Hongwu Tang*, Daiwen Pang. Aptamer functionalized gold nanoparticles based fluorescent probe for the detection of mercury (II) ion in aqueous solution. Talanta, 2013, 113, 26-30. （IF=4.035）
• Xiaojing Xing, Xueguo Liu, Yue He, Yi Lin, Cuiling Zhang, Hongwu Tang*, Daiwen Pang. Amplified fluorescent sensing of DNA using graphene oxide and a conjugated cationic polymer. Biomacromolecules, 2013, 14, 117-123.（IF=5.583）

2012年

• Yue He, Yi Lin, Hongwu Tang*, Daiwen Pang. A graphene oxide-based fluorescent aptasensor for the turn-on detection of epithelial tumor marker mucin 1. Nanoscale, 2012, 4, 2054.（IF=7.760）
• Xiaojing Xing, Xueguo Liu, Yue He, Qingying Luo, Hongwu Tang*, Daiwen Pang. Graphene oxide based fluorescent aptasensor for adenosine deaminase detection using adenosine as the substrate. Biosensors and Bioelectronics, 2012, 37, 61-67. （IF=7.476）

2011年

• Yue He, Zhigang Wang, Hongwu Tang*, Daiwen Pang. Low background signal platform for the detection of ATP: When a molecular aptamer beacon meets graphene oxide. Biosensors and Bioelectronics, 2011, 29, 76-81.（IF=7.476）
• Yue He, Hao Xu, Chuang Chen, Jun Peng, Hongwu Tang*, Zhiling Zhang, Yan Li, Daiwen Pang. In situ spectral imaging of marker proteins in gastric cancer with near-infrared and visible quantum dots probes. Talanta, 2011, 85, 136-141.（IF=4.035）

2010年

• Hao Xu, Chunmei Liu, Yue He, Hongwu Tang*, Qiushui Wu, Study on the chemiluminescence resonance energy transfer between luminol and fluorescent dyes using a linear CCD spectrometer. Journal of Luminescence, 2010, 130, 1872-1879.（IF=2.693）
• Hao Xu, Chuang Chen, Jun Peng, Hongwu Tang*, Chunmei Liu, Yue He, ZeZhong Chen, Yan Li, Zhiling Zhang, Daiwen Pang, Evaluation of the Bioconjugation Efficiency of Different Quantum Dots as Probes for Immunostaining Tumor-Marker Proteins, Applied Spectroscopy, 2010, 64, 847-852.（IF=1.798）